Is this possible? What should be the next course of action after that? FOLFIRI? Is it even possible that both A) the Avastin doesn't work on this particular patient and B) the 5-FU doesn't work either? ***Sorry, I meant to say 4 rounds of treatment, not 4 months. So, it's really 2 months, and the cancer progressed on FOLFOX+Avastin.
Cancer - 5 Answers
Random Answers, Critics, Comments, Opinions :
1 :
The malignancy was progressed way beyond what is considered "curable". Stage 4 cancers are usually treated in order to prolong the life of the patient, by slowing the growth and giving them some time. It doesnt halt the progression. It sounds like a very agressive malignancy.
2 :
It is likely that FOLFIRI would be tried next as they are the first and second –line chemotherapies for advanced colon cancer. The data does not support one should be tired first over the other. It is a little difficult to answer the rest of your question, as I’m not exactly sure what you mean. At the beginning of your question you state the cancer is progressing and toward the end you state the treatment didn’t work. You also didn’t mention how long ago chemo was stopped. Are you saying it did not slow the progression at all? Please understand, I do not mean to be insensitive. I know this must be difficult for you as you obviously care about this person or you would not be on the Internet asking questions. However, I have no way of knowing how much you understand this dreadful disease. The doctors are not trying to cure this person, as they know that is not possible. They are doing their best to give their patient as much time as they can, with the best quality of life. So if the chemo slowed the progression for a while, it did work. I don’t know how long ago they were diagnosed, but you should also know the five year survival rate for stage IV colon cancer is 5%. I am very sorry.
3 :
chemo does not discriminate,kills all-good and bad cells.there might be help at http://411mms.com click on the "about mms" prompt and read it.
4 :
Sweetie, some chemo treatments just don't work and the oncologist has to tweak the treatment. For my Stage III Colon Cancer, I was on FOLFOX + Oxyplatinan. It was not friendly to me and I was only able to last three months on it, or six rounds, then ended up taking Xeloda. It was enough to "so far" (knock on wood) stop the cancer. So, in my situation, my chemo had to be tweaked. Don't pay attention to stats or idiots who quote stats. Each person is different in how they react to cancer and to cancer treatments. There are thousands of Stage III and Stage IV Survivors who have lived past five years out there so just ignore them. The next course of treatment could be anything prescribed by the oncologist--just flow with it and if you question it, get a second opinion and get your mind in the right place to be positive and to mentally combat it. Just remember it isn't unusual to modify or change chemo treatments because they are not responsive to a certain situation. I wish you the best.
5 :
I agree with the poster who said ignore the stats. If I believed my prognosis, I may as well give up. Ignore the states. I'm on Foxflo and it sounds like you need to ask your oncologist about adding another medication. It is hit and miss as to how chemo effects each person. Work with your oncologist and you'll find a treatment plan. Another suggestion is to stay off the internet. Reading all the crap out there will scare you unnecessarily.
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