what's the reason behind colon cancer?
Cancer - 4 Answers
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1 :
you cant just buy it in a store
2 :
Colon Cancer Causes Most colorectal cancers arise from adenomatous polyps—clusters of abnormal cells in the glands covering the inner wall of the colon. Over time, these abnormal growths enlarge and ultimately degenerate to become adenocarcinomas. People with any of several conditions known as adenomatous polyposis syndromes have a greater-than-normal risk of colorectal cancer. In these conditions, numerous adenomatous polyps develop in the colon, ultimately leading to colon cancer. The cancer usually occurs before age 40 years. Adenomatous polyposis syndromes tend to run in families. Such cases are referred to as familial adenomatous polyposis (FAP). Celecoxib (Celebrex) has been FDA approved for FAP. After 6 months, celecoxib reduced the mean number of rectal and colon polyps by 28% compared to placebo (sugar pill) 5%. Another group of colon cancer syndromes, termed hereditary nonpolyposis colorectal cancer (HNPCC) syndromes, also run in families. In these syndromes, colon cancer develops without the precursor polyps. HNPCC syndromes are associated with a genetic abnormality. This abnormality has been identified, and a test is available. People at risk can be identified through genetic screening. Once identified as carriers of the abnormal gene, these people require counseling and regular screening to detect precancerous and cancerous tumors. HNPCC syndromes are sometimes linked to tumors in other parts of the body. Also at high risk for developing colon cancers are people with any of the following: Ulcerative colitis or Crohn colitis (Crohn disease) Breast, uterine, or ovarian cancer now or in the past A family history of colon cancer The risk of colon cancer increases 2-3 times for people with a first-degree relative (parent or sibling) with colon cancer. The risk increases more if you have more than one affected family member, especially if the cancer was diagnosed at a young age. Other factors that may affect your risk of developing a colon cancer: Diet: Whether diet plays a role in developing colon cancer remains under debate. The belief that a high-fiber, low-fat diet could help prevent colon cancer has been questioned. Studies do indicate that exercise and a diet rich in fruits and vegetables can help prevent colon cancer. Obesity: Obesity has been identified as a risk factor for colon cancer. Smoking: Cigarette smoking has been definitely linked to a higher risk for colon cancer. Drug effects: Recent studies have suggested that estrogen replacement therapy and nonsteroidal anti-inflammatory drugs such as aspirin may reduce colorectal cancer risk.
3 :
Frankie has answered this question fairly well. FAP, Prolonged Pan UC, HNPCC, Strong family history could be few of the reasons why one gets it. Still large number of cases are seen without many risk factors. One should consult the Surgeon if One has recently altered bowel habits, Bloody or spurious diarrhoea. .If one is worried he can get his stool checked. Colonoscopy can be reserved for some. Embarrassment or fear should never be cause for anybody's death
4 :
There hasn't been any research yet that directly links lifestyle or genetics to colon cancer. There is a higher incidence if a relative has had ulcerative colitis or colon cancer, which indicates some genetic link, but research is ongoing. Colon cancer affects all sorts of people - from the large and wobbly, to the healthy-eating slim ones...and everything in between.
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