Cancer - 2 Answers
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1 :
In clinical trials, Avastin and Erbitux has improved the mean survival times for metastatic colon cancer (15 months to 22 months) . This means that for most people it is effective. This does not mean it is a cure. It also does not mean everyone benefits. Avastin and Erbitux work against tumor angiogenesis. In other words, it attacks the tumor's blood supply. This is done by binding VEGF, EGFR, PDGF proteins which the tumor secretes to recruit blood vessels. The net effect is dead/shruken and fewer blood vessels to the tumor. Hence, slower growth. These drugs are often used in conjunction with chemotherapy drugs for maximum effectiveness.
2 :
am not sure about erbitux, but i am on avastin and iriticane, for metatastic colon cancer, ( i had colon surgery in 2004, this year they found spots in my lymph nodes ), i had a catscan on friday and will see dr. tomorrow, wed, 2/28/07 to find results of using that combo of drugs. I am hoping for some, if not major reduction of the spots..i have had 4 doses of chemotherapy.
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